IRCCS San Raffaele, Milan


Milan, Italy


IRCCS San Raffaele of Milan


with Manens-Tifs


Detailed and final proposals, supervision of works


High-level biocontainment

High complexity

IRCCS San Raffaele, Milano
IRCCS San Raffaele, Milano

Between 2018 and 2021, Gruppo San Donato completed a series of interventions on several units at the IRCCS San Raffaele in Milan, with the aim of enhancing the diagnostic and therapeutic areas as well as the laboratories and the dedicated areas for anatomo-pathology and research.
As part of this general redevelopment and modernisation process, a new high-tech hybrid room was built in the Cardio-thoracic-vascular surgical unit. The modern integrated room allows to perform highly complex surgical operations involving multidisciplinary teams of different specialists, and has been equipped with medical equipment capable of communicating with video conferencing technologies, high-resolution images of the operating scene with large screens and touch screen control.

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The need to act in accordance with ministerial directives resulting from the spread and worsening of the Covid-19 pandemic emergency led to the upgrade of the morgue area of the IRCCS San Raffaele and, in particular, to the construction of a BSL3 autopsy room for performing biopsies with high safety standards. The room was equipped with systems capable of ensuring a minimum of 6 and a maximum of 12 air changes per hour, negative pressure with respect to the adjacent areas and air outflow directly outside the structure itself or through HEPA filters in the case of recirculation.


Project area:
2.270 sqm
Bed capacity:
Project date:
2018 - 2020
Date of construction:
€ 5.312.000


- High biocontainment capacity
- High complexity

The management of the building site, which was fully operational during the pandemic, was also particularly challenging.
The same issues were faced during the construction of the Biobank in the Dibit building. The new laboratory consists of an area for the preparation and temporary storage of tissues and biological materials with adjoining service areas (washing, c-store, offices) and a 'Cell Factory' laboratory to support the Neuroimmunology Unit.
The central position of the cryopreservation room (in which the freezers and nitrogen cryogenic system are located) allows the laboratories located on the perimeter to be assisted, thus maximising efficiency. All spaces have been designed in relation to the specific containment levels required by the type of activity performed, with the infectious agent laboratory and the dedicated laboratory for genetically modified microorganisms (GMM) achieving BSL3 classification.

IRCCS San Raffaele, Milano